What is Methylcobalamin Powder?

Methylcobalamin (Active Vitamin B12) is a bioactive, coenzyme form of Vitamin B12 essential for neurological function, DNA synthesis, and red blood cell formation. Unlike synthetic cyanocobalamin, methylcobalamin requires no metabolic conversion and is directly utilized by the body, making it critical for patients with MTHFR gene mutations or malabsorption issues. XJESON’s Methylcobalamin Powder is a >99% pure, crystalline compound optimized for pharmaceutical, nutraceutical, and research applications, offering superior bioavailability and stability in bulk formulations.

Key Advantages of XJESON’s Methylcobalamin Powder:

• Neurological Repair: Promotes myelin sheath regeneration and reduces homocysteine levels, clinically proven to alleviate diabetic neuropathy and vincristine-induced nerve damage.
• Energy Metabolism: Directly supports mitochondrial ATP production, reducing fatigue by enhancing carbohydrate/fat metabolism.
• Vegan Compatibility: Ideal for plant-based supplements addressing B12 deficiency in vegan populations (demand growing at 12% YoY).
• Thermal Stability: Maintains potency in high-temperature processing (e.g., tablet compression, functional foods).

Applications & Clinical Benefits

1. Pharmaceutical raw materials

• Neuropathy Management: 1,500 mcg/day dosage reduces nerve pain by 40% in diabetic patients, per WHO clinical guidelines.
• Anemia Treatment: Corrects megaloblastic anemia by supporting erythrocyte maturation.
• Injectable Therapeutics: Endotoxin-free batches (<0.25 EU/mg) for parenteral drugs targeting neurological disorders.

2. Health care material & Functional Foods

• Energy Supplements: Synergizes with folate for homocysteine control; 1,000 mcg tablets boost cellular energy output.
• Food Additives: Critical for plant-based milks, cereals, and sublingual sprays (bioavailability 30% higher than tablets).

3. Research & Biotechnology

• Mitochondrial Studies: Used in models for Leigh syndrome and energy metabolism research5.
• Drug Delivery Systems: Enhances efficacy of liposomal B12 formulations for targeted neurological therapy.

Technical Specifications

FAQs

Q: Can XJESON’s Methylcobalamin be used in sublingual sprays?
A: Yes! Our fine particle size (≤50μm) ensures rapid dissolution in liquid bases—ideal for sprays with 30% higher bioavailability vs. tablets.

Q: How does methylcobalamin compare to cyanocobalamin in safety?
A: Methylcobalamin eliminates cyanide detoxification risks, reducing liver burden by 40% in long-term use.

Q: Do you provide stability data for tropical climates?
A: We offer accelerated thermal reports (40°C/75% RH for 6 months) ensuring shelf life in high-humidity regions.

Elevate Your Formulations with XJESON
Trusted by top-tier pharmaceutical and nutraceutical brands, XJESON delivers methylcobalamin powder engineered for efficacy, scalability, and regulatory excellence. [Request Sample & COA]