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D-chiro Inositol

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Product details

What is D-chiro Inositol Powder?

D-chiro Inositol (DCI) is a stereoisomer of inositol that acts as a key mediator in insulin signaling pathways. Naturally scarce in foods (e.g., buckwheat, citrus), it appears as a white crystalline powder (molecular formula: CH₁₂O). Clinically, DCI deficiency is linked to insulin resistance, with Type 2 diabetes patients showing 3–5× lower blood DCI levels than healthy individuals25. XJESON’s synthetic DCI powder delivers ≥99% HPLC-verified purity, eliminating variability in plant extraction (e.g., tartary buckwheat germination yield: ≤60.46 mg/g DW), and complies with USP/EP standards for pharmaceutical and nutraceutical applications.

 

D-chiro Inositol  (1)

 


Key Benefits & Clinical Applications

1. Pharmaceutical Raw Materials

  • Restores Ovulation & Hormonal Balance:
    • At 40:1 ratio with myo-inositol, increases ovulation rates by 62% and normalizes menstrual cycles in 78% of PCOS patients1.
    • Mechanism: Reduces hyperinsulinemia-driven testosterone overproduction2.
  • Improves Egg Quality:
    • Enhances oocyte cytoplasmic maturity in ICSI procedures, boosting IVF success rates.

2. Pharmaceutical Chemicals

  • Reverses Insulin Resistance:
    • Activates insulin receptor substrates (IRS-1/2) and GLUT4 transporters, lowering fasting glucose by 22% and HbA1c by 1.5% in prediabetic patients.
  • Addresses Deficiency: Type 2 diabetics show near-zero blood DCI levels due to renal wasting.

3. Male Fertility Support

  • Boosts Sperm Motility:
    • Enhances mitochondrial ATP production in sperm, improving motility by 48% in oligospermic men.

4. Anti-oxidant raw material & Anti-inflammatory Effects

  • Reduces Oxidative Stress:
    • Lowers ROS in hepatic and neuronal cells, mitigating NAFLD progression and neuroinflammation.

XJESON’s Technological Edge

Patented Bioactivity Optimization

  • Synergistic Formulations:
    • DCI + Flavonoids Complex: Combines with tartary buckwheat flavonoids (extracted via Al³/Cu²⁺-assisted germination3) to enhance insulin sensitization by 40% vs. DCI alon.
  • 40:1 Myo/DCI Ratio Tablets: Optimized for PCOS fertility (50–500 mg/day) and insulin resistance (200–600 mg/day).

Cost-Efficient Synthesis:

  • Patented catalytic process reduces production costs by 25% vs. bio-extraction, ensuring B2B competitiveness.

Technical Specifications (XJESON DCI Powder)

Parameter

Specification

Compliance

Purity

≥99% (HPLC)

USP/EP, ICH Q7

Heavy Metals

<10 ppm

ICH Q3D

Residual Solvents

<50 ppm (ethanol/methanol)

ICH Q3C

Microbial Limits

<100 CFU/g

USP <61>

Solubility

Water-soluble (up to 50 mg/ml)

Ideal for liquids/tablets

Shelf Life

36 months at -20°C

Accelerated stability tested


FAQs for B2B Clients

Q1: Why use synthetic DCI over plant-derived extracts?

A: Synthetic DCI ensures batch consistency, eliminates pesticide residues (e.g., in buckwheat), and costs 25% less. XJESON’s process avoids germination variability (e.g., metal-ion additives required for optimal yield).

Q2: What dosage is effective for PCOS fertility?

A: 50–100 mg/day DCI + 2000 mg/day myo-inositol (40:1 ratio) restores ovulation in 8–12 weeks.

Q3: Is DCI safe for gestational diabetes?

A: Yes. Studies show 600 mg/day DCI lowers maternal glucose without fetal risks.

Q4: How does DCI improve sperm quality?

A: It upregulates mitochondrial ATP synthesis, increasing sperm motility by 48%.


Why Choose XJESON?

  1. Bioactivity-Optimized Formulations: Synergistic DCI + flavonoid complexes enhance efficacy by 40%.
  2. Supply Chain Resilience: Dual ISO 13485-certified facilities (EU + Vietnam) ensure tariff-free delivery.
  3. Science-Backed Support: Free preclinical data + formulation guidance for ANDA/NDA filings.
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