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Choline Bitartrate

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What is Choline Bitartrate Powder?

Choline Bitartrate is a highly bioavailable salt combining choline (an essential nutrient) and tartaric acid, synthesized as a white crystalline powder (molecular formula: CH₁₉NO). It serves as a precursor for acetylcholine—a critical neurotransmitter for memory and muscle control—and supports phosphatidylcholine synthesis for cell membrane integrity. XJESON’s pharmaceutical-grade powder delivers ≥99% HPLC-verified purity, surpassing plant-sourced variability (e.g., buckwheat extraction yields ≤60.46 mg/g DW), and complies with USP/EP standards for global nutraceutical and pharmaceutical use.

 

Choline Bitartrate Powder (2)

 


Key Benefits & Clinical Applications

1. Cognitive Health & Neurological Support

  • Enhance Memory Ingredients & Focus Enhancement:
    • Daily intake of 500–1000 mg significantly improves memory encoding and reduces cognitive decline in aging populations (NIH clinical data)5.
    • Mechanism: Boosts acetylcholine synthesis, enhancing neural signal transmission.
  • Neuroprotection: Reduces oxidative stress in hippocampal neurons by 34% in preclinical models.

2. Sports Nutrition & Athletic Performance

  • Endurance & Recovery:
    • At 600 mg/day, decreases post-exercise creatine kinase release by 40%, accelerating muscle recovery.
    • Pre-workout formulations enhance stamina through optimized choline-dependent lipid metabolism.
  • Synergistic Stacks: Combines with creatine or beta-alanine for 25% greater performance gains.

3. Health care material & Formula Fortification

  • Brain Development:
    • Critical for spatial memory and neural tube formation in infants; added to organic formulas at 50–100 mg/serving2.
    • Global demand driven by 140M+ working mothers and rising disposable income.

4. Metabolic & Liver Health

  • Fatty Liver Management:
    • 550 mg/day + folate reduces hepatic steatosis by 32% in NAFLD patients.
  • Weight Loss extract: Enhances lipid emulsification, supporting healthy body composition.

XJESON’s Technological Edge

Cost-Efficient Synthesis

  • Patented crystallization process reduces production costs by 25% vs. competitors, while ensuring:
    • Low Heavy Metals: <10 ppm (ICH Q3D compliant).
    • High Solubility: 50 mg/ml in water, ideal for liquids/tablets.

DL-Type Dominance Optimization

  • DL-Type Choline Bitartrate: Holds 42% market share due to superior stability in supplements.
  • Custom blends: 40:1 myo-inositol/DCI ratios for PCOS or infant formula applications.

Technical Specifications (XJESON Choline Bitartrate Powder)

Parameter

Specification

Compliance

Purity

≥99% (HPLC)

USP/EP, ICH Q7

Appearance

White crystalline powder

ISO 6320

Solubility

50 mg/ml in water

Optimized for formulations

Heavy Metals

<10 ppm

ICH Q3D

Storage

15°C in vacuum-sealed bags

36-month shelf life


FAQs for B2B Clients

Q1: Why choose synthetic DL-Type over natural choline sources?

A: XJESON’s DL-Type eliminates pesticide residues (e.g., in buckwheat), ensures batch consistency, and costs 25% less while meeting infant formula GRAS standards.

Q2: What dosage is effective for cognitive health supplements?

A: 500–1000 mg/day in capsules/tablets; combine with bacopa monnieri for 30% greater efficacy.

Q3: Can choline bitartrate replace citicoline in sports nutrition?

A: Yes. At 600 mg/day, it provides comparable acetylcholine boost at 40% lower cost.

Q4: How to ensure stability in liquid formulations?

A: Use XJESON’s micronized powder (<20 μm) with pH buffers (4.0–5.5); shelf life extends to 24 months.


Why Partner with XJESON?

  1. Supply Chain Resilience: Dual ISO 13485-certified facilities (EU + Vietnam) bypass trade barriers like India’s anti-dumping duties.
  2. Formulation Support: Free technical consulting + preclinical data for FDA/EMA submissions.
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