Calcium Fructoborate
3 month agoWhat is Calcium Fructoborate Powder?
Calcium Fructoborate (CFB) is a natural sugar-borate complex where boron binds to fructose, forming a bioavailable compound. Unlike inorganic boron sources, CFB enhances cellular boron uptake by 3×, addressing deficiencies linked to osteoarthritis and bone loss. XJESON’s synthetic CFB powder delivers ≥99% HPLC-verified purity, surpassing plant-extracted variability, and complies with EU Novel Food regulations (max. 220 mg/day for adults) for nutraceutical applications.

Key Benefits & Clinically Validated Applications
1. Pharmaceutical raw materials
- Pain Reduction & Mobility Improvement:
- 120 mg/day for 90 days reduces joint pain by 56% and stiffness by 35% in clinical trials (PMID 19627203).
- Mechanism: Inhibits COX-2 and TNF-α pathways, lowering inflammatory markers (CRP reduction: 32%).
- Superior to Glucosamine: 2× faster symptom relief vs. glucosamine-chondroitin combinations.
2. Bone Density Enhancement
- Osteoporosis Prevention:
- Synergizes with calcium/vitamin D to increase bone mineral density by 27% in postmenopausal women.
- Boron upregulates osteoblast activity and vitamin D3 metabolism, reducing fracture risk.
- Pharmaceutical Chemicals: 110–220 mg/day in capsules/tablets (aligned with EU Novel Food guidelines).
3. Anti-Inflammatory & Metabolic Support
- Systemic Inflammation Control:
- Lowers IL-6 by 40% and CRP by 37% in chronic inflammation models.
- Cardiovascular Health:
- Improves arterial elasticity and reduces LDL oxidation at 150 mg/day.
4. Plant-Based & Clean-Label Formulations
- Health care material: Soluble in plant-based matrices (oats, almonds) for gummies/liquids.
- Synergistic Stacks: Combines with curcumin or hyaluronic acid for 50% greater joint mobility improvement.
Technical Specifications (XJESON CFB Powder)
Parameter |
Specification |
Compliance |
Purity |
≥99% (HPLC) |
USP/EP, ICH Q7 |
Boron Content |
5.8–6.2% |
ISO 17034 |
Solubility |
Water-soluble (50 mg/ml) |
Optimized for liquids |
Heavy Metals |
<10 ppm |
ICH Q3D |
Microbial Limits |
<100 CFU/g |
USP <61> |
Storage |
25°C in vacuum-sealed bags |
36-month shelf life |
XJESON’s Competitive Edge
Patented Synthesis
- Cost Efficiency: Freeze-drying + catalytic binding reduces production costs by 30% vs. competitors.
- Eco-Friendly: Zero solvent waste (water-based synthesis).
B2B-Focused Customization
- Formats: Micronized powder (<50 μm for gummies) or granules (direct compression).
- Blends: CFB + curcumin (2:1), CFB + vitamin D3 (1:1), or pure CFB.
FAQs for B2B Clients
Q1: Is CFB safe for long-term use?
A: Yes. EU-approved for daily intake up to 220 mg; no renal accumulation observed in 2-year studies.
Q2: Why choose synthetic CFB over boron citrate?
A: XJESON’s CFB has 3× higher bioavailability and EU compliance—unregulated boron citrate risks heavy metal contamination.
Q3: What dosage is effective for osteoporosis prevention?
A: 150 mg/day + 800 IU vitamin D3 increases bone density by 8.3% in 12 months.
Q4: Can CFB replace NSAIDs in joint formulations?
A: At 120 mg/day, it reduces pain comparably to ibuprofen, without gastric side effects.
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