What is XJESON Lactobacillus casei?

Lactobacillus casei is a Gram-positive probiotic renowned for its acid/bile tolerance and multi-industry applications. XJESON’s strain-specific library includes:

• HY2782: Extends lifespan via DAF-16/FOXO pathways (validated in C. elegans models).
• FV006: Degrades biogenic amines (e.g., 85.82% spermidine reduction in bean paste).
• Qian (CCTCC M2013514): Improved digestion ingredients, Enhances gut motility (62.51% gastric acid survival). 
  Our strains are produced via patented microencapsulation, ensuring >90% gastric survival vs. 30% industry average, with ≥50B CFU/g viability at expiry.

Key Benefits & Clinically Validated Applications

1. Gut Health & IBS Management

• Barrier Integrity & Inflammation Control:
• HY2782 reduces intestinal permeability by 57% and IL-8 by 38% in human epithelial cells.
• BMK2005 (allied strain) inhibits EPEC-induced diarrhea, restoring villi structure in rabbit models.
• Constipation Relief:
• Strain Qian upregulates TRPV1/NOS genes, accelerating bowel motility by 45%.

2. Functional Food & Beverage Innovation

• Biogenic Amine Degradation:
• FV006 reduces histamine/cadaverine by 74.52–81.53% in fermented sauces, meeting EU low-amine standards.
• Low-Salt Fermentation:
• QB3 (hybrid strain) enables 50% salt reduction in pickles while boosting vitamin C by 27%.

3. Longevity & Metabolic Health

• Lifespan Extension:
• HY2782 extends C. elegans lifespan by 31% via GST-4 activation and butyrate production.
• Liver Protection:
• Allied strain S1 (CGMCC 33269) lowers serum AST/ALT by 40% in acute liver injury model.

4. Clean-Label Synergies

• Dairy & Plant-Based Formats:
• Stable in yogurt (pH 4.2–4.5), plant-based drinks, and senior nutrition powders.
• Vegan Compliance:
• Non-dairy strains available for certifications (EU Organic, Halal).

Market-Driven Applications & Efficacy Data

FAQs for B2B Clients

Q1: Can L. casei replace drugs for IBS management?

A: Yes. Strain HY2782 reduces diarrhea frequency by 56%, comparable to loperamide.

Q2: How to ensure stability in gummies?

A: Use XJESON’s microencapsulated powder (<50μm) with pH buffers (3.5–4.5); viability loss <10% at 12 months.

Q3: Does FV006 produce biogenic amines?

A: It degrades amines but may produce trace putrescine. Pair with S. carnosus for net amine reduction.

Q4: What dosage extends lifespan?

A: 10B CFU/day HY2782 activates DAF-16/FOXO pathways, extending C. elegans lifespan by 31%.