What is Lactobacillus paracasei?

Lactobacillus paracasei is a Gram-positive, facultative anaerobic probiotic bacterium within the Lactobacillus casei group, renowned for its exceptional acid/bile tolerance and genomic plasticity. First isolated from dairy ecosystems, it thrives in diverse habitats—from human GI tracts to fermented foods—through unique evolutionary adaptations:

XJESON's strain-specific portfolio targets high-growth markets:

• TK1501 (CCTCC M 206133): Enhances isoflavone aglycone content in fermented soy milk (genistein ↑25.34×, daidzein ↑43.97×), with α-glucosidase inhibition (IC50: 1.89 mg/ml) for diabetes management.
• CNCM I-1572: Delivers ≥1B CFU/dose for gut flora rebalancing, FOS-fiber synergism.
• ATCC® 334™: Industrial-grade strain for functional foods with 99% EPEC inhibition6.
  Production: Patented microencapsulation ensures >95% gastric survival and ≥50B CFU/g stability at 24-month expiry.

Key Benefits & Clinically Validated Applications

1. Oral Health & Pathogen Inhibition

• Caries Prevention:
• Strain TK1501 reduces Streptococcus mutans biofilm by 92%, cutting dental caries incidence by 42%.
• Effective in toothpaste, mouthwash, and chewable tablets (patented application CN101190239B).
• Periodontal Protection:
• Live TK1501 suppresses Porphyromonas gingivalis growth by 85% (in vitro).

2. Functional Food Additives

• Fermented Soy Milk:
• TK1501 boosts bioactive isoflavones (genistein ↑25.34×), enhancing antidiabetic effects.
• Low-Salt Fermentation:
• Jlus66 strain enables 30% salt reduction in pickles while inhibiting Listeria.

3. Animal Nutrition & Antibiotic Alternatives

• Pharmaceutical Chemicals:
• Reduces Salmonella colonization by 73% in poultry feed (DSM 32264).
• Livestock Productivity:
• Cuts piglet diarrhea incidence by 68% as feed additive.

4. Immune health care material & Gut Barrier Support

• Inflammation Control:
• CNCM I-1572 + FOS blend improves IBS symptoms (49% lower bloating at 10B CFU/day).
• Barrier Repair:
• Jlus66 upregulates occludin synthesis by 300%, reducing intestinal permeability.

Technical Specifications (XJESON Strains)

XJESON's Competitive Edge

Strain-Specific IP

• TK1501: Patented isoflavone-activating enzymes for fermented soy milk.
• Jlus66: Engineered salt-tolerance genes (halotolerance ↑40%).

Supply Chain Resilience

• EU/US warehouses bypass India’s 25% probiotic tariffs.
• -18°C global shipping (O₂ transmission <0.005 cc/m²/day).

B2B Customization

• Blends: e.g., TK1501 + soy isoflavones for antidiabetic drinks; CNCM I-1572 + FOS for gut health sachets.
• Certifications: Halal, Kosher, NSF, ISO 13485, Non-GMO.

FAQs for B2B Clients

Q: Can TK1501 replace preservatives in fermented drinks?
A: Yes. Its bacteriocin secretion inhibits spoilage microbes, extending shelf life by 30%.

Q: What dosage prevents dental caries?
A: 5B CFU/g in chewing gum, used twice daily for 3 weeks (42% caries reduction).

Q: How to maintain viability in animal feed pelleting?
A: XJESON’s microencapsulated powder (<100μm) withstands 80°C for 15s (viability loss <5%).