Meta Description

Professional supplier of Calcium L-5-Methyltetrahydrofolate (L-5-MTHF-Ca), active folate ingredient for prenatal, multivitamin and nutraceutical formulations. COA, GMP and export support available.

Calcium L-5-Methyltetrahydrofolate 

Active Folate Ingredient for Nutraceutical & Supplement Formulations

Stable Active Folate Solution for Premium Supplements

We support global nutraceutical brands with reliable sourcing, quality documentation and export coordination for active folate ingredients.

• Active Folate Source
• Prenatal & Women's Health Applications
• COA & Third-Party Testing Support
• OEM/ODM Compatible

   

  

  what is Calcium L-5-Methyltetrahydrofolate?

  Calcium L-5-Methyltetrahydrofolate, also known as L-5-MTHF Calcium, is the biologically active form of folate used in dietary supplements and functional nutrition products.

  It is widely applied in:

  • Prenatal nutrition
  • Women's health supplements
  • Multivitamin formulations
  • Active folate products
  • Homocysteine management formulas

  Compared with conventional folic acid, L-5-MTHF is considered a premium folate ingredient for advanced nutraceutical formulations.

  

Applications

Prenatal Supplements

Used in pregnancy and maternal nutrition formulations.

Multivitamin Products

Suitable for premium vitamin blends and daily wellness products.

Functional Nutrition

Commonly used in active folate and methylation support formulas.

Capsules, Tablets & Powder Blends

Compatible with multiple supplement delivery systems.

Product Specifications

 

Item	Specification
Product Name	Calcium L-5-Methyltetrahydrofolate
Synonym	L-5-MTHF Calcium
Appearance	Light Yellow Powder
Assay	95%+
CAS No.	151533-22-1
Grade	Food Grade
Test Methods	HPLC
Packaging	1kg / 5kg / 25kg Drum

COA 

 

Test Item	Specification	Test Result	Method
Physical Properties	—	—	—
Appearance	White to pale yellow crystalline powder	Complies	Visual
Identification (HPLC/IR)	Consistent with reference standard	Complies	HPLC/IR
Chemical Assay	—	—	—
Assay (L-5-MTHF-Ca, anhydrous)	95.0% ~ 102.0%	99.20%	HPLC
D-Isomer	≤ 1.0%	0.35%	HPLC
Calcium Content	7.0% ~ 8.5%	7.80%	Titration
Water Content	≤ 17.0%	8.50%	Karl Fischer
Related Substances	≤ 2.5%	0.80%	HPLC
Heavy Metals & Impurity	—	—	—
Lead (Pb)	≤ 2.0 mg/kg	< 1.0 mg/kg	ICP-MS
Arsenic (As)	≤ 1.0 mg/kg	< 0.5 mg/kg	ICP-MS
Residual Solvents	Complies with USP <467>	Complies	GC
Microbiology	—	—	—
Total Aerobic Bacteria	≤ 1000 CFU/g	< 100 CFU/g	Microbial Culture
Yeast & Mold	≤ 100 CFU/g	< 10 CFU/g	Microbial Culture
E. coli	Negative	Negative	Microbial Test
Salmonella	Negative	Negative	Microbial Test

Why Brands Work With Us

Sentian Bio provides free samples, OEM/ODM customized products, and professional technical support. Contact us anytime 

We connect global supplement brands with reliable Chinese ingredient manufacturing resources.

Our support includes:

• Integrated sourcing
• Quality control coordination
• Export documentation
• Third-party testing support
• OEM/ODM cooperation
• Stable supply chain management

FAQ

Is Calcium L-5-Methyltetrahydrofolate the same as folic acid?

No. L-5-MTHF is the active form of folate commonly used in premium nutraceutical products.

What documents can you provide?

We can support:

• COA
• Specification Sheet
• MSDS
• Heavy Metal Testing
• Microbiological Testing

What packaging options are available?

Standard export packaging includes 1kg foil bags and 25kg drums.

Can you support OEM/ODM projects?

Yes. We support raw material supply as well as customized supplement manufacturing solutions.

Looking for a Reliable Active Folate Supplier?

Contact us for:

• Latest quotation
• Technical documents
• Sample support
• OEM/ODM cooperation