DRUG NAME:Florfenicol Powder
ACTIVE INGREDIENTS:Florfenicol Powder
CHARACTER:This product is white or white powder
PHARMACOLOGICAL ACTION:Pharmacodynamics Flufenicol is a broad spectrum antibiotic in the aminoalcohol class, a bacteriosuppressor that acts by binding to the ribosome 50S subunit to inhibit the synthesis of bacterial proteins. It has strong antibacterial activity against a variety of gram-positive and Gram-negative bacteria. Pasteurella hemolyticus, Pasteurella multocida and actinobacillus pleuropneumoniae were highly sensitive to flufenicol. In vitro, the antibacterial activity of flufenicol against many microorganisms is similar or stronger than that of sulfoxamycin, and some bacteria that are resistant to aminools due to acetylation, such as Escherichia coli and GramBacillus pneumoniae leiberii and others may still be sensitive to flufenicol. It is mainly used for the bacterial diseases of pigs, chickens and fish caused by sensitive bacteria, such as Pasteurella hemolyticus, Pasteurella multocida and actinobacillus pleuropneumoniae caused by bovine and pig respiratory diseases. Typhoid and paratyphoid caused by salmonella, chicken cholera, chicken white dysentery, E. coli, etc.; Fish Pasteurella, Vibrio, staphylococcus aureus, hydroomonas,enteritis and other bacteria caused by fish bacterial septicemia, enteritis, erythroderma and so on.The absorption of flufenicol is rapid, and the therapeutic concentration can be reached in the blood after about 1 hour, and the peak blood concentration can be reached in 1 to 3 hours. The bioavailability is over 80%. Flufenicol is widely distributed in animals and can cross the blood-brain barrier. It is mainly excreted in the urine in its original form, and a small amount is excretedin the stool.
DRUG INTERACTION:(1) Macrolides and Lincoamines have the same target as this product, they are bound to the 50S subunit of bacterial ribosomes, and can produce antagonistic effects when combined.
(2) may antagonize the bactericidal activity of penicillins or aminoglycosides, but has not been demonstrated in animals.
FUNCTION AND USE:Aminoalcohol antibiotics. Used for bacterial diseases caused by Pasteurella and Escherichia coli.
USAGE AND DOSAGE:For every 1kg of body weight, 0.4 ~ 0.6g for pigs and chickens, twice a day,
for 3 ~ 5 days; Fish 0.2 ~ 0.3g, once a day, for 3 ~ 5 days.
ADVERSE REACTION:(1) This product has a certain immunosuppressive effect when used at higher than the
recommended dose.
(2) There is embryoFetal toxicity, use with caution during pregnancy and lactation.
MATTERS NEEDING ATTENTION:
(1) The laying period of laying hens is prohibited.
(2) Vaccination period or severe deficiency of immune functionThings prohibited.
(3) Animals with renal insufficiency should be appropriately reduced or extended administration interval time.
WITHDRAWAL PERIOD:Pigs 20 days, chickens 5 days, fish 375 °days.
SPECIFICATION:10%
PACKAGE:100g/ can
LAY BY:Keep out of light and sealed.
SHELF LIFE:Two years
APPROVALNUMBER:Veterinary medicine190182538
PRODUCTION ENTERPRISE:Guangzhou Nongfeng Animal Pharmaceutical Co. ,LTD.