22
5 year ago
Orlistat is a non-systemic effects of anti-obesity drugs for specific gastrointestinal lipase inhibitor, combined with dietary restrictions can help promote weight loss and prevent weight regain. Gastrointestinal lipases break down fats in the gastrointestinal tract is necessary enzymes, orlistat inhibits stomach, pancreatic and hydroxy acid esterase, primarily through the stomach, small intestine lumen of the stomach and pancreatic lipases active serine parts form a covalent bond, to inactivate enzymes play a therapeutic role.
Product name
Orlistat
Cas
96829-58-2
Brand
Iknow
Appearance
White Powder
Specification
99%
Type
Raw Materials
Package
1Kg/25Kg/Drum or As per your request
Storage
Store in cool and dry places ,keep away from strong light
Shelf life
2 years when properly stored
Safety
Non-toxic, non-stimulating, safe and reliable
Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrolipstatin is widely used for the treatment of obesity.
Specification:
Item
Specification
Result
Appearance
while powder
white powder
Identification
HPLC retention time
Conforms
Melting Point
42 ºC -45°C
42 ºC -45°C
Specific optical rotation
-31.0°~-41.0°
-36.0°
Purity optical rotation
-31.0°~-41.0°
-36.0°
Total impurity
no more than 2.0%
1.6%
Max Individual impurity
no more than 0.5%
0.3%
Water content%(K&F)
no more than 0.5%
0.1%
Residual solvents
EtOH no more than 0.5%
N.D
EtAC no more than 0.5%
N.D
n-Heptane no more than 0.5%
less than 0.1%
Residue on ignition
less than 0.2%
0.10%
Heavy metals
no more than 20ppm
less than20ppm
Assay (HPLC)
no less than 99.0%
99.60%
Conclusion
Meets the Requirements
1) Orlistat is used with a low-calorie diet to help you lose weight and to maintain your weight after weight loss.
2) Orlistat is in a class of drugs called lipase inhibitors. It works in your intestines, where it blocks some of the fat you eat from being absorbed and digested. This undigested fat is then removed in your bowel movements .
3) Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.
Minoxidil Powder, known as 6 - (1-piperidinyl) - 2,4-pyrimidine diamine-3-oxide, is an organic compound with white or almost white crystalline powder. It can directly relax vascular smooth muscle, has a strong role in small artery dilation, reduces peripheral resistance and blood pressure, and has no effect on volume vessels, so it can promote venous reflux. Antihypertensive drugs for refractory, primary or renal hypertension. It is used to prevent fat hair loss and animal husbandry.
Gabapentin Powder is a white to grayish white crystalline powder with stable chemical properties at normal temperature and pressure. It is an additional treatment for epilepsy patients with localized seizures which can not be satisfactorily controlled or tolerated by conventional antiepileptic drugs and epilepsy patients with localized seizures and then generalized.
Berberine hydrochloride is mainly used in the treatment of gastroenteritis, bacillary dysentery and other intestinal infections, eye conjunctivitis, suppurative otitis media, etc. Recently, it has been found that this product has blocking effect α- Receptor, antiarrhythmic effect.
Quercetin Powder is a flavonol compound with many biological activities. It can directly inhibit tumor and effectively play the role of cancer prevention and anti-cancer; It also has strong biological activity in antibacterial, anti-inflammatory, anti allergic and preventing diabetic complications. In addition, quercetin Powder can also reduce blood pressure, enhance capillary resistance, reduce capillary fragility, lower blood lipid, expand coronary artery, increase coronary blood flow and so on. It also has adjuvant treatment effect on patients with coronary heart disease and hypertension. Quercetin is nontoxic. Therefore, it is of great significance for the treatment and prevention of cancer, aging and cardiovascular diseases, and has great development value.
Kaempferol powder is mainly used for anticancer, fertility inhibition, antiepileptic, anti-inflammatory, antioxidant, antispasmodic, anti ulcer, cholagogic diuretic and antitussive.
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