Camptothecin powder

12 month ago

14 0 

Shaanxi Changsheng Industrial Co., Ltd.

3 year

Product details

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Camptothecin Powder 98% Bulk - High-Purity Herbal Extract for Pharmaceuticals, Nutraceuticals & Research

Product Overview

Camptothecin Powder 98% is a premium Plant Extract & Herbal Extract derived from the roots, bark, and fruits of Camptotheca acuminata—a rare endemic plant native to China. As a naturally occurring alkaloid with potent biological activity, this product is widely recognized as a critical raw material for Nutritional Supplements, pharmaceutical formulations, and biotech research. Our bulk supply offering stands out for its ultra-high purity (minimum 98% via HPLC), natural and sustainable sourcing, and rigorous quality control systems, making it the preferred choice for global pharmaceutical manufacturers, supplement brands, and research institutions.

Key highlights include: exceptional bioactivity, seamless compatibility with Peptide Powder, Vitamins Powder, and other bioactive ingredients, scalable bulk supply capacity, and full compliance with international standards—delivering consistent performance and cost-efficiency for your production and research needs.

Technical Specifications

Purity: Minimum 98% (HPLC verified)
Appearance: Light yellow to off-white fine powder
Molecular Formula: C20H16N2O4
Molecular Weight: 348.35 g/mol
Melting Point: 264-267°C (decomposes)
Solubility: Soluble in dimethyl sulfoxide (DMSO), slightly soluble in ethanol, insoluble in water
Heavy Metal Content: Total (Pb, Cd, Hg) ≤10 ppm
Microbial Limit: Total Aerobic Microbes ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli: Not detected
Residue Solvents: Meets USP/EP standards (≤5000 ppm)
Storage Condition: Sealed, cool (15-25°C), dry, and light-protected environment
Shelf Life: 24 months under recommended storage conditions

Product Images and Videos

Product Image (98% Purity)

Camptothecin Powder 98% Bulk High Purity Herbal Extract

Quality Testing & Application Demo Video

Watch our exclusive video to view HPLC purity testing, safe handling procedures, and formulation integration demos. (Insert YouTube video embed code here)

Product Features & Advantages

Core Biological Mechanism

Camptothecin exerts its effects by selectively inhibiting topoisomerase I—an enzyme essential for DNA replication, transcription, and repair in rapidly dividing cells. By stabilizing the DNA-topoisomerase I complex, it induces irreversible DNA strand breaks, triggering apoptosis (programmed cell death) in abnormal cells (e.g., tumor cells) and suppressing viral replication. This mechanism also supports immune modulation by regulating immune cell proliferation and activity.

Key Product Features

Ultra-High Purity (98%): Exceeds industry standard (typically 95%), minimizing impurities that compromise end-product safety or efficacy
Natural & Sustainable Sourcing: Derived from organically cultivated Camptotheca acuminata with eco-friendly extraction processes (no harmful solvents)
Multi-Functional Bioactivity: Combines anticancer, immune-modulating, and antiviral properties—versatile for cross-industry applications
Superior Compatibility: Synergizes with Peptide Powder, Vitamins Powder, immune checkpoint inhibitors, and other Plant Extracts
Rigorous Quality Assurance: Every batch undergoes HPLC purity testing, heavy metal screening, microbial analysis, and stability testing
Stable Formulation: Low degradation rate under recommended storage and processing conditions (compatible with standard manufacturing workflows)

Competitive Advantages

Scalable Bulk Supply: 1kg-1000kg order capacity with consistent lead times (7-15 working days) – no supply shortages
Customizable Purity: 95%-99% purity options tailored to specific pharmaceutical, supplement, or research needs
Vertical Integration: From raw material cultivation to finished product – no middlemen, 15-20% cost savings for buyers
Global Compliance: Meets GMP, ISO 9001:2015, USP, and EP standards for direct use in drug formulations
Traceability: Full batch documentation (raw material origin, production date, test reports) for regulatory compliance

Usage Guidelines

Pre-Use Preparation: Store Camptothecin Powder in sealed packaging under recommended conditions (15-25°C, dry, light-protected) to preserve potency. Allow the powder to reach room temperature (20-25°C) before opening to avoid moisture absorption.
Precise Weighing: Use a calibrated analytical balance to measure the required quantity. Typical dosage ranges: 0.1%-5% in formulations (adjust based on application – pharmaceutical, supplement, or research).
Dissolution & Mixing: Dissolve the powder in a compatible solvent (e.g., DMSO, ethanol) at a concentration of 10-50 mg/mL. Stir gently at low temperature (≤30°C) to avoid degradation, then gradually mix with other ingredients (e.g., Peptide Powder, Vitamins Powder, or Nutritional Supplements).
Formulation Integration: Incorporate the mixture into your end product (capsules, tablets, injectables, or functional foods) following standard production protocols. Avoid high temperatures (>60°C) and prolonged exposure to light during processing.
Quality Verification: Conduct final purity (HPLC) and stability testing of the finished product to ensure compliance with your specifications and international standards.

Application Scenarios

Pharmaceutical Industry

Primary raw material for anticancer drug formulations targeting colorectal, gastric, liver, bladder, and cervical cancers. Compatible with chemotherapy agents and immune checkpoint inhibitors to enhance therapeutic efficacy. Meets GMP standards for direct use in injectables, oral formulations, and targeted drug delivery systems.

Nutraceutical & Nutritional Supplements

Formulated into immune-support supplements to maintain immune system balance, especially for populations at risk of viral infections. Can be combined with Vitamins Powder, Peptide Powder, and other Herbal Extracts to create multi-functional health products (e.g., immune-boosting capsules, antiviral supplements).

Biotech & Research Institutions

Widely used in preclinical and clinical research on cancer treatment, viral replication mechanisms, and immune modulation. Ideal for in vitro (cell culture) and in vivo (animal model) experiments, as well as drug discovery and development projects.

Emerging Applications

Explored for use in Cosmetic Raw Materials (anti-aging formulations) due to its cell-regulating properties, and in veterinary medicine for animal health products. (Note: Confirm regulatory compliance for non-pharmaceutical/nutraceutical applications in your target market.)

Value for Buyers

Cost Efficiency: Bulk supply and direct factory pricing reduce raw material costs by 15-20% compared to small-batch suppliers.
Efficacy Enhancement: 98% purity ensures higher bioactivity, improving end-product performance (e.g., higher tumor inhibition rate, stronger immune support).
Market Expansion: Versatile applications enable entry into high-growth sectors (anticancer drugs, immune health supplements) with a trusted Plant Extract.
Regulatory Peace of Mind: Full compliance with global standards reduces regulatory risks for market entry in the US, EU, and Asia.
Supply Stability: Long-term sourcing contracts and large inventory ensure consistent supply, avoiding production delays.

Certifications and Compliance

ISO 9001:2015 Quality Management System Certification
GMP (Good Manufacturing Practices) Certification for Pharmaceutical Raw Materials
FDA Registration (US Market Access)
REACH Compliance (EU Chemical Regulation)
Non-GMO Certification
Halal & Kosher Certified (Optional for Custom Orders)
USP/EP Compliance (Pharmaceutical Grade Standards)
Environmental Management System Certification (ISO 14001)

Customization Options

Purity Customization: 95%-99% purity levels available to meet specific application requirements (pharmaceutical, supplement, research).
Packaging Solutions: Aluminum foil bags (100g/500g/1kg), fiber drums (25kg/50kg), or customer-specified packaging with private labeling.
Formulation Support: Technical assistance for blending with Peptide Powder, Vitamins Powder, or other Plant Extracts to optimize synergistic effects.
Batch Size Flexibility: MOQ as low as 1kg, with preferential pricing for large-volume orders (≥50kg).
Documentation Customization: Customized COA (Certificate of Analysis), MSDS, and regulatory documents for target markets.

Production Process

Raw Material Selection: Handpicked Camptotheca acuminata roots, bark, and fruits from organic plantations. Strict pre-extraction testing for heavy metals, pesticides, and moisture content.
Eco-Friendly Extraction: Advanced ethanol-water solvent extraction to isolate Camptothecin alkaloids, ensuring high yield and minimal environmental impact.
Purification: Column chromatography and recrystallization processes to concentrate and refine the extract to 98%+ purity, removing impurities and byproducts.
Quality Control Testing: HPLC analysis for purity verification, atomic absorption spectrometry for heavy metals, microbial testing, and solubility testing.
Packaging & Preservation: Vacuum-sealed aluminum foil bags (inner) + moisture-proof fiber drums (outer) with desiccants. Labeling includes batch number, production date, and expiry date.
Storage & Shipping Preparation: Temperature-controlled warehouses (15-25°C) with humidity monitoring. Pre-shipment inspection for packaging integrity.
Traceability Documentation: Comprehensive batch records (raw material origin, production parameters, test results) for full traceability from farm to finish.

Frequently Asked Questions

Q1: Is Camptothecin Powder 98% compatible with other bioactive ingredients like Food Additives or Plant Oil?

A1: Yes, it exhibits excellent compatibility with most Food Additives, Plant Oil, Peptide Powder, and Herbal Extracts. Our technical team can provide tailored formulation guidance to optimize synergistic effects and avoid compatibility issues.

Q2: What is the lead time for bulk orders (≥100kg) and can expedited shipping be arranged?

A2: Standard lead time for 98% purity bulk orders is 7-10 working days. For customized purity or packaging, lead time is 10-15 working days. Expedited production (3-5 working days) is available for urgent orders with additional fees. International shipping via DHL/FedEx takes 3-7 working days.

Q3: How is the product protected during transportation to ensure stability?

A3: We use insulated, moisture-proof packaging with desiccants and temperature monitors. For long-distance or warm-climate shipments, cold chain packaging (15-25°C) is available. All shipments include a COA and MSDS for customs clearance.

Q4: Can I request a sample for quality testing before placing a bulk order?

A4: Yes, we offer 10g-50g samples with a nominal fee (fully refundable upon bulk order placement). Sample delivery takes 3-5 working days via DHL/FedEx. Each sample includes a mini COA for preliminary testing.

Q5: Does your product meet EU REACH and US FDA requirements for pharmaceutical use?

A5: Yes, our Camptothecin Powder 98% is fully REACH compliant (registered under EU chemical regulations) and FDA-registered for use in pharmaceutical raw materials. We provide complete regulatory documentation to support your market entry.

Q6: Can you provide customized packaging with our brand logo?

A6: Yes, we offer private labeling and customized packaging (bags, drums) with your brand logo, product information, and regulatory details. Minimum order quantity for custom packaging is 50kg.

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