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China gromwell root extract 95% shikonin 517-89-5

7 month ago
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Natural Colorants of China gromwell root extract 95% shikonin 517-89-5
What is shikonin​?
Shikonin is a red naphthoquinone compound derived from the roots of the plant Lithospermum erythrorhizon, also known as red gromwell. The Shikonin plant of antibacterial ingredients has been used in traditional Chinese medicine for centuries for its various medicinal properties, including antibacterial and anti-inflammatory effects. 
What does shikonin powder do?
Besides their use as pigments, shikonin and its derivatives have been used as a medicine for antimicrobial, anti-inflammatory and anti-tumor purposes. They also have shown the ability to heal wounds, burns and hemorrhoids via proliferation of granulation tissue.
How does shikonin kill cancer cells​?
Shikonin of herbal extract possesses antitumor capabilities by modulating a plethora of pathways, such as triggering apoptosis, autophagy, necroptosis, ferroptosis, halting the cell cycle, overcoming drug resistance, and potentiating the impact of chemotherapy.
What part of cellular respiration is affected by shikonin?
Shikonin primarily affects cellular respiration by impairing mitochondrial function and interfering with the electron transport chain (ETC). Specifically, it can inhibit Complex II (CII) of the ETC, reducing ATP production. Shikonin can disrupt the mitochondrial membrane potential and induce reactive oxygen species (ROS) generation, leading to mitochondrial dysfunction and potential apoptosis.
 
 
Shikonin-4
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