Raw material production workshop

Pharmaceutical workshop in the present construction demand accounted for a relatively large, the chemical raw materials extraction of it is relatively complex, today we are combining characteristics of pharmaceutical chemical raw materials to produce and design key points, take you to analyse the general layout, the layout of pharmaceutical chemical raw materials workshop, etc., summarizes the problems need attention in design. 1. Development background and current situation of API industry: In recent years, China's pharmaceutical industry has developed rapidly, and the production of API has maintained a relatively good momentum of development. 2. Production characteristics and design points of API workshop: In the design process of API production workshop, it is necessary to set up the flammable and explosive area centrally, and isolate this area from other areas with explosion-proof walls, and set up good ventilation/exhaust system and electrical alarm system in this area; For the API manufacturing plant, regardless of whether the reaction itself needs reflux, as long as the reaction needs high temperature heating or there is a large amount of heat release during the reaction, the condensation reflux system should be considered in the design; For the reaction kettle or gas cylinder with high pressure safety hazard, safety valve overpressure relief measures should be taken to meet the safety production requirements. In addition, consideration should be given to GMP requirements in reaction zones for API synthesis. For example, relatively independent storage areas for raw materials (or chemical raw materials) and dry storage areas for reaction intermediates should be set up in the synthesis reaction area of active substances to avoid cross-contamination of materials. In a word, chemical apis are both drugs and chemical products, and should meet the design requirements of both. Not only to ensure the safety of personnel and production, reduce the risk of environmental pollution, but also to meet the requirements of GMP, drying and packaging areas to meet the corresponding clean level requirements, while reducing the risk of cross-contamination in each area.